Rare but potentially critical complications are cardiac arrest, abnormal heart rhythms, severe low blood pressure, seizures, and neuroleptic malignant syndrome. The most common effects of overdose are drowsiness and tachycardia.
Treatment protocols and support should follow the same as for any structurally related tricyclic, such as tricyclic antidepressants. ĭysphagia, a life-threatening side-effect, may rarely occur. In general, the National Committee for Quality Assurance recommends avoiding the use of cyclobenzaprine in the elderly because of the potential for more severe side effects. Some experts believe that cyclobenzaprine should be avoided in elderly patients because it can cause confusion, delirium, and cognitive impairment. Īgitation is a common side effect observed, especially in the elderly. The sedative effects of cyclobenzaprine are likely due to its antagonistic effect on histamine, serotonin, and muscarinic receptors. Drowsiness and dry mouth appear to intensify with increasing dose.
Side effects Ĭyclobenzaprine results in increased rates of drowsiness (38%), dry mouth (24%), and dizziness (10%). It may also be used along with other treatments for tetanus.
A 2009 Cochrane review found insufficient evidence to justify its use in myofascial pain syndrome. Ī 2004 review found benefit for fibromyalgia symptoms, with a reported number needed to treat of 4.8 (meaning that 1 person out of every 4.8 benefits from treatment) for pain reduction, but no change in fatigue or tender points. It is not useful for spasticity due to neurologic conditions such as cerebral palsy. Since no benefit is proven beyond that, therapy should not be continued long-term. It decreases pain in the first two weeks, peaking in the first few days, but has no proven benefit after two weeks. Cyclobenzaprine is used to treat such muscle spasms associated with acute, painful musculoskeletal conditions. After sustaining an injury, muscle spasms to stabilize the affected body part occur, which may increase pain to prevent further damage. May be akin to Old English clyppan and modern English clip.Cyclobenzaprine is used, in conjunction with physical therapy, to treat muscle spasms that occur because of acute musculoskeletal conditions. Of unknown origin, it could be onomatopoetic.
#Clyppan alternative full#
* Spoken form, usually not written in writing, the unappended plural form (optionally followed by the full pronoun) is preferred. ** the mediopassive present participle is extremely rare and normally not used it is never used attributively or predicatively, only for explicatory subclauses Klippa ( weak verb, third-person singular past indicative klippti, supine klippt) Klippa ( third person singular past indicative klipti, third person plural past indicative kliptu, supine klipt)Ĭonjugation Conjugation of klippa (group v-9nn)ġOnly the past participle being declined.
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