The majority of cases worldwide in 2012 were in the South-East Asia (29%), African (27%) and Western Pacific (19%) regions. In 2013, an estimated 9.0 million people developed TB and 1.5 million died from the disease, 360 000 of whom were HIV-positive. Tuberculosis (TB) remains one of the world’s deadliest communicable diseases. "Immunomodulator Potential of Miana Leaves( Coleus s cutellar i oides (L) Benth) in Prevention of Tuberculosis Infection." American Journal of Microbiological Research 3, no.
Result, Results showed the increasing of T-lymphocytes, CD4 T-Cells, the levels of IFN-γ, TNF-α and decreasing in the number of M.
tuberculosis colonies derived from the rat lung in LJ media. In this study we measure the level of Immunomodulatory parameter the number of T-lymphocytes and CD4 T-cells measured by flowcytometry method, the levels of IFN-γ and TNF-α were measured by ELISA and the number of M. tuberculosis H37Rv strain and subsequently given a placebo, EDM and GAB (combined Rifampicin and EDM) and healthy control animals were treated with EDM. Aim, The aim of this study to investigate the immunonomodulator effects of miana leaves ( Coleus s cutellar i oides (L) Benth) on prevention of tuberculosis in wistar rats, Method, Samples of white male Wistar rats were divided into 4 groups, the samples were treated with miana leaves extract (EDM) and then infected by intra tracheal M.
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